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Blog / Pacific International Resources

The Ultimate Mega-Guide to Manuka Honey: Science, Potency, and the MGO Standard

The Ultimate Mega-Guide to Manuka Honey: Science, Potency, and the MGO Standard

In the world of superfoods, few items carry as much prestige—or as much confusion—as Manuka honey. It’s been hailed by celebrities, studied by world-class scientists, and stocked in the wellness cabinets of biohackers and health enthusiasts globally.

But what exactly is it? Why does one jar cost $15 while another costs $160? And most importantly, how do you know if the jar in your hand is the real deal?

In this comprehensive guide, we’re breaking down everything you need to know about Manuka honey, from the chemistry of MGO to the strict New Zealand government standards that protect every drop.

 


 

1. The Manuka Story: A Rare Gift from Nature

Manuka honey isn't made by a special kind of bee; it’s made from a special kind of flower. The Manuka bush (Leptospermum scoparium) is native to the rugged landscapes of New Zealand.

What makes it so rare? The Manuka flower only blooms for 2 to 6 weeks per year.

Weather conditions must be perfect for the bees to collect the nectar. If it’s too rainy or too windy, the harvest is lost. This incredibly short window—combined with the unique chemistry found only in this nectar—is why authentic Manuka honey is one of the most sought-after natural substances on Earth.

 


 

2. The Power of MGO: The Only Number That Matters

While all honey has some level of antibacterial activity (usually from hydrogen peroxide), Manuka is in a league of its own. Its "superpower" comes from Methylglyoxal, or MGO.

MGO is the compound responsible for Manuka’s stable, non-peroxide activity. Unlike other honeys, where the "magic" can be destroyed by heat or light, MGO is incredibly resilient.

  • The Evolution of Grading: In the past, the industry used various trademarks like UMF™ or KFactor to guess at potency. Today, the science has evolved. MGO is the direct, transparent measurement of the honey’s bioactive strength.

  • The Conversion: MGO is formed naturally in the hive as the honey ages. The higher the MGO number on your jar, the more concentrated those bioactive properties are.

  • The Science: Research in Frontiers in Microbiology confirms that MGO is the primary driver of Manuka’s unique antimicrobial profile.

 


 

3. The "Gold Standard": The NZ MPI Government Test

How do you know you aren't just buying "Manuka-flavored" clover honey?

In 2017, the New Zealand Ministry for Primary Industries (MPI) established the world’s most rigorous scientific definition for Manuka honey. To be legally exported as "Manuka" from New Zealand, the honey must pass a laboratory "fingerprint" test that identifies:

  1. Four specific chemical markers.

  2. A DNA marker from Manuka pollen.

This MPI standard is the leading authority on authenticity. When you buy honey that meets these government requirements, you aren't just trusting a brand—you’re trusting a national law that protects the integrity of the honey.

 


 

4. Top Wellness Benefits Supported by Science

🍯 I. Superior Respiratory & Throat Support

Manuka honey is a "staple" during seasonal shifts for a reason. Its viscous texture coats the throat, while the MGO provides a natural layer of support.

  • The Study: A landmark review in BMJ Evidence-Based Medicine found that honey is often superior to conventional "usual care" for improving upper respiratory tract symptoms.

🦷 II. A Win for Oral Wellness

While sugar is usually the enemy of teeth, Manuka honey acts as a microbial balancer. It targets the bacteria associated with plaque and gum irritation without harming the healthy bacteria in your oral microbiome.

✨ III. Skin Clarity & Soothing

Dermatologists have used "Medical-Grade" Manuka for years. It draws moisture into the skin (humectant) while maintaining a low pH that supports the skin's natural barrier.

🦠 IV. Digestive Balance & Prebiotic Support

Your gut is an ecosystem. Manuka honey acts as a prebiotic, providing the "fuel" your beneficial gut bacteria need to thrive.

  • The Study: Laboratory trials published in Phytotherapy Research show that Manuka can effectively inhibit problematic digestive bacteria in a controlled environment.

 


 

5. Choosing Your MGO: A Simple Guide

Because we focus on MGO as the true measure of potency, choosing a jar is simple:

  • MGO 100+ (Maintenance): Perfect for a daily wellness boost in your tea, smoothies, or on toast.

  • MGO 300+ (Targeted Support): The "sweet spot" for digestive support or helping a scratchy throat.

  • MGO 500+ (Maximum Potency): Ideal for intensive immune support or as a topical application for skin blemishes.

  


 

6. How to Use Manuka Honey Like a Pro

To get the most out of your "Liquid Gold," avoid boiling it. Extreme heat can degrade the delicate enzymes.

  • The Morning Ritual: Stir a teaspoon of MGO 300+ into warm (not hot!) lemon water to prime your digestion for the day.

  • The Pre-Workout: Take a spoonful straight for a clean, natural energy boost.

  • The DIY Face Mask: Apply a thin layer to clean skin for 15 minutes to soothe redness and lock in moisture.

 


 

The Verdict: The Power of the Hive

If you are looking for a simple sweetener, regular honey is fine. But if you are looking for a functional food backed by the New Zealand MPI's strict standards and proven MGO potency, Manuka is in a league of its own.

 


 

Ready to find your perfect MGO grade? Shop Our MPI-Certified, High-MGO Manuka Collection Here

 


 

Regulatory Safety Disclaimer

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with a healthcare professional before starting any new supplement.




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Group display of Manuka oil, propolis extract, and oral throat sprays on wooden tray

Everything You Need To Know About Propolis

1. The Basics
2. The Compounds that Make it Special
3. What is a Certified CL level
4. Propolis Tincture Vs. Propolis Extract
5. Uses of Propolis:
    5a - Burn & Wound Treatment
    5b - Acne & Other Skin Concerns
    5c - Oral Health
    5d - Cold & Flu Symptoms
    5e - Diabetes Management
    5f - Brain Health
    5g - Gut Health
    5h - Upper Respiratory Infections
    5i - Natural Antibiotic
    5j - Candida
    5k - Nail Infections
6. How to Use Propolis & Our Top 5 Propolis DIYs
7. Disclaimers & Known Interactions

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1. The Basics

Propolis is a bee-made resin using plant resins, a bit of honey, and a little bee saliva. They use it to fill in small cracks in the beehive. It also helps maintain the hive temperature, prevents predators from entering, and protects against dangerous microbes and fungi.

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2. What Compounds Make Propolis Special?

Over 500 compounds have been found in propolis so far!! Many of them have anti-inflammatory benefits, but which compound is the superstar?  Flavonoids. 

Flavonoids are a type of antioxidant that has beneficial anti-inflammatory effects, and they protect your cells from oxidative damage that can lead to disease. Propolis is a super concentrated form of antioxidants. 

So, beyond the concentration, what makes the antioxidants in propolis different from, say, the ones found in blueberries? The bees do, of course! 

The mixture of plant resins, honey, and bee saliva adds antibacterial and antiseptic properties that simply cannot be matched!

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3. What is Certified CPL Level?

The certified CPL level ensures that you get a high, consistent level of flavonoids per gram of the finished product. Because propolis must first be broken down with alcohol and then with water, and all propolis has naturally varying levels of flavonoids, we must blend and test them to achieve consistent levels. This means you always know you are getting therapeutic levels of flavonoids in every bottle of  P.R.I. propolis.

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4. Propolis Extract Vs. Propolis Tincture

Propolis extract is water-based, while the tincture is alcohol based. You might have read that extracts are more potent than tinctures; however, with our certified CL levels, you will get the same potency no matter which base you choose. 

In its base form, Propolis can only be broken down with alcohol. The extract is then put into large vats and continuously beaten with water until the alcohol dissipates.  

We recommend the tincture for external uses like cuts, bites, acne, and wounds, but the extract is much more versatile and an excellent choice for small children and those who cannot consume alcohol. 

Additionally, if your recipe is oil-based, such as face oil, use the tincture, as the extract will not blend with the oil. 

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5. Uses of Propolis

Ancient cultures used propolis to treat wounds and abscesses on the skin and mouth. It was even used in the first and second World Wars to prevent infections and speed healing. Since then, we’ve found many more wonderful uses of propolis. Here we will attempt to cover them all:

5a - Burn & Wound Treatment 

As mentioned above, propolis has been used on wounds for quite some time, but our knowledge of how it works and its applications have expanded. Researchers tested propolis against several dangerous microbes and have found it very effective against aggressive bacteria.

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5b - Acne & Other Skin Concerns 

Propolis’ complex anti-inflammatory, antibacterial and antioxidant properties make for an excellent natural acne treatment and preventative. Propolis is now in many skincare products & has proven to help lock in moisture and regenerate the skin. One study showed that propolis could reverse UV damage to the skin. Additionally, a combination of Olive Oil, Beeswax, Propolis, and Honey has been found very effective against diaper rash. 

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5c - Oral Health 

Over the last several years, the link between overall health and our oral health has become impossible to ignore. This knowledge and growing concern about fluoride exposure and toxicity has increased the popularity of natural oral care options. Did you know that children ingesting fluoride toothpaste are the #1 reason for poison control calls? (1) (2) Unbiased studies show fluoride doesn’t prevent any harmful bacteria, now is the time to switch to a natural oral care routine. Propolis has shown to be a fantastic natural addition to oral care that will actively fight harmful bacteria. Recent studies show it can also help protect against oral disease, reduce plaque and treat canker sores. 

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5d - Cold & Flu Symptoms 

The antiviral and antibacterial properties of propolis have made it a common natural treatment for cold & flu symptoms worldwide. It has even recently been studied against COVID. While further studies must be done, initial studies show that propolis may be part of a very effective treatment. 

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5e - Diabetes Management

Propolis was first acknowledged in 1988 to act in an anti-hyperglycemic capacity, thus stabilizing blood sugar glucose. Since then, many more studies have shown that propolis may inhibit enzymes that increase blood sugar. 

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5f - Brain Health

Propolis is showing great promise in treating many brain conditions ranging from detoxification, oxidative stress,  neuroinflammation, brain injury, Alzheimer’s disease, Parkinson’s disease, epilepsy models, depression, cytotoxicity, cognitive improvement, and brain infections. These benefits are thought to be caused by propolis’ unique and highly potent anti-inflammatory properties.

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5g - Gut Health

Studies on propolis and gut health abound, showing great promise in the treatment of many conditions as well as general maintenance. A rich source of probiotics, propolis acts in our gut, much the same way as it does in the hive, creating an intestinal barrier and preventing toxins and bacterial dislocation from the gut to the blood. Propolis also has shown great success in treating GI diseases such as oral mucositis, oral microbiota, ulcerative colitis, and gastric ulcers.

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5h - Upper Respiratory Tract Infections (URTIs)

Many studies have been done on children and adults, showing that propolis is highly effective against URTIs. URTIs are ubiquitous, especially in children; some have become antibiotic-resistant. Current drugs for treatment are high in cost and have serious side effects in children. Propolis is shown to work on antibiotic-resistant infections. 

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5i - Natural Antibiotics

While we’ve touched on this above, it is essential to note this use, especially since more bacteria are becoming resistant to antibiotics. Probiotics are crucial while on antibiotics. Propolis is a powerful probiotic and natural antibiotic in one! Not only shown to protect against the spread of harmful bacteria, but propolis can also prevent it from taking hold to begin with. Studies indicate that this is because propolis can break down and prevent the spread of biofilms, which harmful bacteria use to take hold and spread. 

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5j - Candida

While this could fall under gut health and skin health, we thought it necessary to highlight, given that candida is found in most of the population. There are different types of candida, such as Candida albicans, which typically manifests in the genitals and mouth, and Candida tropicalis, which occupies the intestinal tract. Studies show that propolis is effective against many candida types.

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5k - Nail Infections

The most popularly prescribed treatment for fungal nail infections is resistant to seven common nail funguses AND not nearly as effective as propolis on the non-resistant fungi.

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6. How to use propolis and our top 5 ways to use it!

Propolis is best taken in the morning. While there are no official dosage recommendations, ½ - 1 dropper daily is ideal. Place the propolis under your tongue and allow it to dissolve. Those who dislike the flavor recommend placing the propolis in a glass of juice. Drink slowly.

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6a - Antibacterial Alcohol-Free Mouthwash

Ingredients:

Put all ingredients in a bottle and shake before use. Avoid swallowing. If swallowing is a concern, such as with young children, simply remove the manuka oil from the recipe.

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6b - Propolis & Manuka Oral Spray

Ingredients:

Combine all ingredients in the spray bottle and shake. Spray as needed for sore throat, fresh breath, or after meals when you can’t brush.

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6c - Propolis & Manuka Diaper Rash Treatment

Ingredients: 

Mix all ingredients. Clean and thoroughly dry the affected area. Apply ointment to the affected area and allow it to dry slightly before diapering. Honey & propolis are safe to use externally on children of all ages, provided they do not have an allergic reaction to bee products.

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6d - Steroid Free Nasal Spray

Ingredients:

Shake or blend all ingredients. Use it in your Neti Pot or a similar device. 

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6e - Three Ingredient Facial Oil

Ingredients:

Add essential oils and propolis to the dropper bottle. Fill the rest of the way with the Manuka in Sweet Almond Oil. Shake well before each use. 

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7. Disclaimers and Known Drug Interactions 

As always, we strive to provide you with the best information backed by scientific studies. However, we are not doctors and cannot recommend any treatment for specific concerns. It’s important to talk to your doctor about any concerns you might have. 

That said, here is what we think you need to know:

Propolis has no known severe, serious, moderate, or mild interactions with other drugs. Take caution when combining propolis with medications that slow blood clotting (Anticoagulant / Antiplatelet drugs). Propolis is thought to slow blood clotting, though more studies need to be conducted on the topic.

Allergic reactions (skin or respiratory symptoms) may occur, particularly in people who are allergic to bees or bee products.

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